Synthesis, Structure, and Antioxidant Activity of Tri and Di-organotin Carboxylate Complexes of Tryptophan

Abdulhadi, Mohanad Ali; Mohammed, Khaldoon Jasim; Baqir, Sadiq J.; Hadi, Angham G.

doi:10.30492/ijcce.2022.546226.5097

Synthesis, Structure, and Antioxidant Activity of Tri and Di-organotin Carboxylate Complexes of Tryptophan

Document Type : Research Article

Authors

¹ Medical Laboratory, Techniques Departement, Al-Maarif university college, Anbar, IRAQ

² Department of Medical Instrumentation Technologies Engineering, Hilla university college , Babylon , IRAQ

³ Medical Laboratories Techniques Department, Al‐Mustaqbal University College, Babylon, IRAQ

⁴ Department of Chemistry, College of Science, University of Babylon, Babylon, IRAQ

10.30492/ijcce.2022.546226.5097

Abstract

Three organotin carboxylate complexes were synthesized by condensation of the reaction of methanolic tryptophan solution with Tri, and Diorganotin chloride for 3-4 hours to obtain the corresponding complexes (1-3) with good yields. These complexes were also diagnosed with several techniques, including infrared spectroscopy, Sn¹¹⁹,and proton NMR, in addition to elemental analysis of the elements. These complexes were applied to find out the antioxidative activity of tryptophan and the prepared complexes by using DDPH and CUPRAC techniques. The results of the antioxidant activity in both ways showed that the prepared complexes are more effective than tryptophan from which they are derived. Also, complex 1 showed more anti-oxidant activity than other complexes.

Keywords