Synthesis of New 10-Arylthioanthralins and Oxidation of Thioanthralins to Their Corresponding Sulfones

Document Type : Research Article


1 Department of hemistry, Faculty of Science, Urumia University, Pstcode 57154, Urumia, I.R. IRAN

2 Departent of Chemistry, Manchester University, Manchester, M13 9PL, ENGLAND



Treatment of 10-bromoanthralin (1) with several thiophenols (2) gave the corresponding 10-arylthioanthralins (3) in high yields. Oxidation of thioanthralins (3a-c) and (3k-m) using an excess of m-chloroperbenzoic acid gave the corresponding sulfones (4a-c) and (4k-m) in good yields. Oxidation of thioanthralins (3d-f) gave a mixture of the corresponding sulfones (4d-f) and anthralin-10,10'-dehydrodimer (5). Oxidation of thioanthralins (3g-j) afforded only anthralin-10,10'-dehydrodimer (5) with no evidence of sulfone.


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