Determination of Selected Heavy Metals in Air Samples and Human Health Risk Assessment in Tehran City, Iran

Document Type : Research Article

Authors

School of Environment, College of Engineering, University of Tehran, Tehran, I.R. IRAN

Abstract

Heavy metal contamination has become a global issue. In this study, the concentrations of arsenic (As), lead (Pb), nickel (Ni), zinc (Zn), chromium (Cr), copper (Cu), and cadmium (Cd) in the air of the Tehran metropolis were measured. Also, cancer and non-cancer risk assessments were performed to quantify the rate and effect of infection on health. Sampling was done every month from April 2019 to March 2020 for one year. Sampling points in the whole city were determined based on Municipality 22 districts of Tehran. The concentrations of the studied heavy metals in nanogram per cubic meter ( /m3) showed the following order: Zn (106.22) > Pb (31.65) > Cu (16.38) > As (5.83) > Ni (5.77) > Cr (5.62) > Cd (5.36). The results indicate that in non-carcinogenic risk assessment, the hazard index (HQ) of As (8.20E+00), Ni (8.67E+00), Cr (1.14E+00), and Cd (1.13E+01), and the total hazard index (HI) of 2.94E+01 are above the safe level of 1, indicating the potential threat of non-carcinogenic diseases through the inhalation of air. According to USEPA guidelines, the risk of carcinogenicity is unacceptable for Cr, acceptable for As, Cd, and Ni, and without any significant health effects for Pb. The total carcinogenic risk of metals was 1.10E-02, being in the high-risk range. Therefore, exposure to heavy metals through air inhalation increases the risk of cancer and mortality, so 61 people annually suffer from various cancer types due to the inhalation of air. The Monte Carlo simulation uncertainty results also confirm those of non-carcinogenic and carcinogenic respiratory risk analysis of heavy metals in the air. The obtained results indicate the need for improving the air quality in Tehran needs and taking into account the health risks to humans via inhalation exposure to heavy atmospheric metals.

Keywords

Main Subjects


[1] Arsalani F., Alijani B., Akbari M., Mohammadkhani Sh., Measuring the Rate of Dust Falling and its Spatial Analysis in 22 Districts of Tehran, Natural Geography Research, 51(4): 633-649 (2019).
[3] Azizi G., Ghanbari H., Numerical Simulation of Air Pollutants in Tehran, Based on Wind Patterns by TAPM, Physical Geography Research Quarterly, 41(68):15-32 (2010).
[4] Baltas H., Sirin M., Gökbayrak E., Ozcelik A., EA Case Study on Pollution and a Human Health Risk Assessment of Heavy Metals in Agricultural Soils Around Sinop Province, Turkey, Chemosphere, 241: 125015. (2020).
[6] Cal. EPA (California Environmental Protection Agency). “Technical Support Document for the Determination of Non Cancer Chronic Reference Exposure Levels. Draft for Public Comment”. Office of Environmental Health Hazard Assessment, Berkeley, CA. (1997).
[7] Chambers J.M., Cleveland W.S., Kleiner B., Tukey P.A., “Graphical Methods for Data Analysis”, The Wadsworth Statistics/Probability Series, Duxbury Press (1983).
[8] Cui L., Wu Z., Han P., Taira Y., Wang H., Meng Q., Ma Y., Chemical Content and Source Apportionment of 36 Heavy Metal Analysis and Health Risk Assessment in Aerosol of Beijing, Environmental Science and Pollution Research, 27(7): 7005-7014 (2020).
[10] Engwa G.A., Ferdinand P.U., Nwalo F.N., Unachukwu M.N., Mechanism and Health Effects of Heavy Metal Toxicity in Humans, In Poisoning in the Modern World-New Tricks for an Old Dog? Intech Open. (2019).
[11] Ghorani-Azam A., Riahi-Zanjani B.,  Balali-Mood M., Effects of Air Pollution on Human Health and Practical Measures for Prevention in Iran, Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 21:  (2016).
[12] Goudarzi G., Alavi N., Geravandi S., Idani E., Behrooz H.R.A., Babaei A.A., Mohammadi M.J., Health Risk Assessment on Human Exposed to Heavy Metals in the Ambient air PM 10 in Ahvaz, Southwest Iran, International Journal of Biometeorology, 62(6): 1075-1083 (2018).
        https://doi.org/10.1007/s00484-018-1510-x
[13] Gumy S., Mudu P., News on Air Pollution and Health Data and Impacts on Health from the World Health Organization, Clean Air Journal, 28(1): 6-6 (2018).
[14] Chelani A.B., Gajghate D.G., ChalapatiRao C.V., Devotta S., Particle Size Distribution in Ambient Air of Delhi and its Statistical Analysis, Bulletin of Environmental Contamination and Toxicology, 85(1): 22-27(2010).
        https://doi.org/10.1007/s00128-010-0010-4
[15] Heger, M.,  Sarraf, M. Air pollution in Tehran: Health Costs, Sources, and Policies. World Bank.
       (2018). https://doi.org/10.1596/29909
[16] Hernández-Pellón A., Nischkauer W., Limbeck A., Fernández-Olmo I., Metal (loid) Bioaccessibility and Inhalation Risk Assessment: A Comparison between an Urban and an Industrial Area, Environmental Research, 165: 140-149 (2018).
        https://doi.org/10.1016/j.envres.2018.04.014
[17] Hu B., Wang J., Jin B., Li Y., Shi Z., Assessment of the Potential Health Risks of Heavy Metals in Soils in a Coastal Industrial Region of the Yangtze River Delta, Environmental Science and Pollution Research, 24(24): 19816-19826 (2017).
       https://doi.org/10.1016/j.scitotenv.2017.08.074
[19] Jiang H.H., Cai L.M., Wen H.H., Hu G.C., Chen L.G., Luo J., An Integrated Approach to Quantifying Ecological and Human Health Risks from Different Sources of Soil Heavy Metals, Science of the Total Environment, 701: 134466 (2020).  
[20] Joshirvani A., Samarghandi M.R., Leili M., PM10 Concentration, Its Potentially Toxic Metals Content, and Human Health Risk Assessment in Hamadan, Iran, CLEAN–Soil, Air, Water, 2000174 (2021).
[21] Karimi S., Rezayani N., Determination of Suspended Particulate Matter Concentration and Assessment of Inhalation Risk in the Ambient Air of Ahvaz City, Iran, Asian Journal of Water, Environment and Pollution, 15(2): 57-68 (2018).
[22] Karyab H., “Carcinogen Risk Assessment of Polycyclic Aromatic Hydrocarbons in Drinking Water of Tehran”. Ph.D. Dissertation in Environmental Health Engineering, Faculty of Public Health, Tehran University of Medical Sciences. (2012).
[23] Kermani M., Asadgol Z., Gholami M., Jafari A.J., Shahsavani A., Goodarzi B., Arfaeinia H., Occurrence, Spatial Distribution, Seasonal Variations, Potential Sources, and Inhalation-Based Health Risk Assessment of Organic/Inorganic Pollutants in Ambient Air of Tehran, Environmental Geochemistry and Health, 43(5): 1983-2006 (2021).
        https://doi.org/10.1007/s10653-020-00779-w
[24] Li H.H., Chen L.J., Yu L., Guo Z.B., Shan C.Q., Lin J.Q., Cheng Z., Pollution Characteristics and Risk Assessment of Human Exposure to Oral Bioaccessibility of Heavy Metals via Urban Street Dusts from Different Functional Areas in Chengdu, China, Science of the Total Environment, 586: 1076-1084 (2017).
[25] Li J., Michalski G., Olson E.J., Welp L.R., Larrea Valdivia A.E., Larico J.R., Paredes L.M., Geochemical Characterization and Heavy Metal Sources in PM10 in Arequipa, Peru, Atmosphere, 12(5): 641 (2021).
[26] Liu F., Chen X., Liu Y., Niu Z., Tang H., Mao S., Xiang H., Serum Cardiovascular-Related Metabolites Disturbance Exposed to Different Heavy Metal Exposure Scenarios, Journal of Hazardous Materials, 415: 125590 (2021).
        https://doi.org/10.1016/j.jhazmat.2021.125590
[27] Liu Y., Hu J., Wang X., Jia J., Li J., Wang L., Gao P., Distribution, Bioaccessibility, and Health Risk Assessment of Heavy Metals in PM2. 5 and PM10 During Winter Heating Periods in Five Types of Cities in Northeast China, Ecotoxicology and Environmental Safety, 214: 112071 (2021).
        https://doi.org/10.1016/j.ecoenv.2021.112071
[28] López J.M., Callén M.S., Murillo R., Garcia T., Navarro M.V., De la Cruz M.T., Mastral A.M., Levels of Selected Metals in Ambient Air PM10 in an Urban Site of Zaragoza (Spain), Environmental Research, 99(1): 58-67 (2005).
[29] Melaku S., Morris V., Raghavan D., Hosten C., Seasonal Variation of Heavy Metals in Ambient Air and Precipitation at a Single Site in Washington, DC, Environmental Pollution, 155(1): 88-98 (2008).
[30] Nazari Cheraghi F., “Evaluation of Heavy Metal Pollution in the Surface Soil of Urban Parks in Tehran”, Master Thesis in Natural Resources Engineering - Environment, Faculty of Natural Resources and Earth Sciences, Kashan University. (2015).
[31] Noorpoor A.R., Sadri Jahanshahi A., Evaluation of Health Risk Assessment by Heavy Metals in the Ambient Air of Tehran, Journal of Environmental Studies, 39(4): 181-192 (2014).
        https://dx.doi.org/10.22059/jes.2014.36471
[32] Pardakhti A., “Determination of VOCS Concentration in Fresh Water of Tehran City and Evaluation of Risk for Citizens”, A Ph.D. Dissertation in Environmental Engineering, Faculty of Environment, University of Tehran. (2010).
[33] Pardakhti A.R., Bidhendi G.R.N., Torabian A., Karbassi A., Yunesian M., Comparative Cancer Risk Assessment of THMs In Drinking Water from Well Water Sources and Surface Water Sources, Environmental Monitoring and Assessment, 179(1-4): 499-507 (2011).
[34] Pauselli L., Attademo L., Bernardini F., Compton M., M239. Environmental Pollution and Risk for Psychotic Disorders: An Update, Schizophrenia Bulletin, 46(Suppl 1): S226. (2020).
[35] Rastegar, M., Namini E., Tonekaboni N., “Tehran Air Quality Report” (2020).
        https://doi.org/10.13140/RG.2.2.32871.78244
[36] Rezayani N., Mirmohammadi M., Mehrdadi N., Origin and Risk Assessment, and Evaluation of Heavy Metal Pollution in the Soil and Air of Tehran (Case Study: Central District in Tehran City), International Journal of Environmental Science and Technology, 1-22. (2022).
        https://doi.org/10.1007/s13762-022-03957-8
[37] Rezayani N., Mirmohammadi M., Mehrdadi N., Origin and Risk Assessment, and Evaluation of Heavy Metal Pollution in the Soil of Tehran, Iran. Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 31(9): 3100-3126 (2022).
        https://doi.org/10.30492/ijcce.2021.531021.4759
[38] Rezayani N., “Chemical Composition and Risk Assessment of Particulate Matters Concentrations in the City of Ahvaz, Iran”. Master Thesis in Environmental Engineering, School of Environment, College of Engineering, University of Tehran. (2013).
[39] Sah D., Verma P.K., Kumari K.M., Lakhani A., Chemical Fractionation of Heavy Metals in Fine Particulate Matter and their Health Risk Assessment Through Inhalation Exposure Pathway, Environmental Geochemistry and Health, 41(3): 1445-1458. (2019).
        https://doi.org/10.1007/s10653-018-0223-8
[40] Sielski J., Kaziród-Wolski K., Jóźwiak M.A., Jóźwiak M., The Influence of Air Pollution by PM2. 5, PM10 and Associated Heavy Metals on the Parameters of Out-Of-Hospital Cardiac Arrest, Science of the Total Environment, 788, 147541 (2021).
[41] Tavakoli H., Azari A., Ashrafi K., Salimian M., Momeni M., Human health risk Assessment
of Arsenic Downstream of a Steel Plant in Isfahan, Iran: A Case Study
, International Journal of Environmental Science and Technology, 17(1): 81-92 (2020).
[43] Tsai M.S., Chen M.H., Lin C.C., Liu C.Y., Chen P.C., Children's Environmental Health Based on Birth Cohort Studies of Asia (2)–Air Pollution, Pesticides, and Heavy Metals, Environmental Research, 179, 108754 (2019).
[44] USDoE. RAIS (The Risk Assessment Information System). (2019).
        http://rais.ornl.gov.
[45] USEPA, “Risk Assessment Guidance for Superfund. Volume 1: Human Health Evaluation Manual (Part A)”. U.S. Environmental Protection Agency, Office of Emergency and Remedial Response, Washington. (1989).
[46] USEPA I.R.I.S. “Integrated Risk Information System, Environmental Protection Agency Region I”, Washington DC, 20460. (2011).
[47] USEPA U. “Guidelines for Carcinogen Risk Assessment”. EPA/630/P-03/001F. In Risk Assessment Forum. (2005).
[48] WHO, First WHO Global Conference on Air Pollution and Health, (2018). Available Online at:
[49] Phan C.C., Nguyen T.Q.H., Nguyen M.K., Park K.H., Bae G.N., Seung-bok L., Bach Q.V., Aerosol Mass and Major Composition Characterization of Ambient Air in Ho Chi Minh City, Vietnam, International Journal of Environmental Science and Technology, 17(6): 3189-3198 (2020).
        https://doi.org/10.1007/s13762-020-02640-0
[50] Zhang Q., Yu R., Fu S., Wu Z., Chen H.Y., Liu H., Spatial Heterogeneity of Heavy Metal Contamination in Soils and Plants in Hefei, China, Scientific Reports, 9(1): 1-8 (2019).