Four-Component Reaction between Ethyl Benzoylacetate, Hydroxylamine, Aldehydes and Malononitrile: Synthesis of Isoxazol-5(2H)-Ones


Faculty of Chemistry, University of Mazandaran, Babolsar, I.R. IRAN


We present herein a new and efficient four-component synthesis of isoxazol-5(2H)-ones involving ring closing/Knoevenagel condensation/Michael addition sequential reactions.


Main Subjects

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