Document Type : Research Article
CUNY Graduate Center, Department of Chemistry, Hunter College, New York, N.Y. 10021, USA
Research Division, Hoffimann-La Roche, Inc., Nutly, NJ 07110, USA
Results of the bromination and dehydrobromination of several angular methylated decalindiones are described. The key reaction, base-induced cyclization of the monobromo keto ester (3), and the dibromo ketone (4), leads to the formation of tricyclic systems (6) and (9) respectively.