Effect of Cyclosporin-A on the Order and Dynamics of DPPC model Membrane Systems

Document Type : Research Article


Department of Chemistry, Isfahan University of Technology, Isfahan, I.R. IRAN



Laser Raman spectroscopy has been employed to investigate the effects of cyclosporine-A on the order and dynamics of DPPC (Dipalmytoyl Phosphatidyl Choline) midel membrane system. It is shown that the addition of small amount of cyclosporine-A to a DPPC dispersion disturb the system and changes the order/disorder parameter of the model membrane.


Main Subjects