Effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. As a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. The fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose content inside the granule. Results presented here indicate that as PVP content outside the granule or aerosol fraction inside or outside the granule in the matrix increases, the fractional release increases. The fractional release profiles of diclofenac sodium from matrices, when each ingredient is inside or outside, or half inside - half outside the granule, are compared.
Abdekhodaie, M. J., & Hemmati, A. A. (2002). Influence of Formulation Parameters on the Release of Diclofenace Sodium from Matrices with Manufacturing Formulation Ingredients. Iranian Journal of Chemistry and Chemical Engineering, 21(2), 135-140. doi: 10.30492/ijcce.2002.9624
MLA
Mohammad Jafar Abdekhodaie; Ali Asghar Hemmati. "Influence of Formulation Parameters on the Release of Diclofenace Sodium from Matrices with Manufacturing Formulation Ingredients". Iranian Journal of Chemistry and Chemical Engineering, 21, 2, 2002, 135-140. doi: 10.30492/ijcce.2002.9624
HARVARD
Abdekhodaie, M. J., Hemmati, A. A. (2002). 'Influence of Formulation Parameters on the Release of Diclofenace Sodium from Matrices with Manufacturing Formulation Ingredients', Iranian Journal of Chemistry and Chemical Engineering, 21(2), pp. 135-140. doi: 10.30492/ijcce.2002.9624
VANCOUVER
Abdekhodaie, M. J., Hemmati, A. A. Influence of Formulation Parameters on the Release of Diclofenace Sodium from Matrices with Manufacturing Formulation Ingredients. Iranian Journal of Chemistry and Chemical Engineering, 2002; 21(2): 135-140. doi: 10.30492/ijcce.2002.9624
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