Synthesis of N, N΄3, 4-Dialkylamino-1, 2, 5-Oxadiazoles

Document Type: Research Article

Authors

1 Department of Chemistry, Faculty of Science, University of Lorestan, Khorramabad, Lorestan. I.R. IRAN

2 Department of Biology, Faculty of Science, University of Tarbiat Modares, Tehran. I.R. IRAN

Abstract

N, N΄-3, 4-di(methylamino)-1, 2, 5-oxadiazole (1f) was prepared by dehydration of N, N΄-3, 4-di(methylamino)glyoxime (2f) in aqueous potassium hydroxid at 170-180 ˚C. Under similar conditions N, N΄-3, 4-di(benzylamino)-1, 2, 5-oxadiazole (1c) and N, N΄-3, 4-di(isopropylamino)-1, 2, 5-oxadiazole (1e) were not obtained, but, N, N΄-3, 4-di(ethylamino)-1, 2, 5-oxadiazole (1g) was appeared with small amount. 

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