Voltammetric Determination of Dopamine Using Au Nanoparticles Decorated on Multi-Walled Carbon Nanotubes and β-cyclodextrin Modified Glassy Carbon Electrode

Document Type : Research Article

Authors

Department of Chemistry, Khorramabad Branch, Islamic Azad University, Khorramabad, Iran

Abstract

In the present study, a glassy carbon electrode (GCE) was modified with a nanocomposites of multi-walled carbon nanotubes (MWCNTs) and β -cyclodextrin (CD) and then decorated with gold nanoparticles to obtain the AuNPs- MWCNTs@β-CD/GCE electrode. The AuNPs- MWCNTs@β-CD/GCE electrode was distinguished via field emission scanning electron microscopy (FE- SEM) and cyclic voltammetry (CV). On the one hand, Interaction between MWCNTs and β-CD increased electro- active surface area. On the other hand, decorating AuNPs on MWCNTs@β-CD caused excellent electrical conductivity modified electrode. Further, the synergistic effect between MWCNTs@β-CD and AuNPs notably increment DP oxidation. Differential pulse voltammetry (DPV) was utilized as a method to determine the amount of dopamine (DP).Using the AuNPs-MWCNTs@β-CD/GCE electrode led to in a 26-fold increase in the DP current response compared to the untreated electrode. Under optimized situation, the prepared sensor exhibited good sensitivity for detection DP in two linear ranges of 3.0–26.0 and 32.0–270.0 μM, with a detection limit of 0.85 μM.

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