Development of novel palm resin – poly(acrylamide) based hydrogel silver nanocomposite for antibacterial activity

Articles in Press

Document Type : Research Article

Authors

1 PG & RESEARCH DEPARTMENT OF CHEMISTRY, PRESIDENCY COLLEGE (Autonomous), CHENNAI

2 PG and Research Department of Chemistry, Presidency College (Autonomous), Chennai, Tamil Nadu, India

Abstract

This investigation studies the antibacterial action of a novel palm resin – poly(acrylamide) based hydrogel silver nanocomposite. Palm resin based semi-interpenetrating hydrogel networks (SIH) were synthesised through an improved free radical polymerisation of acrylamide in the presence of palm resin using N,N-methylene bisacrylamide (MBA) as the cross-linker, ammonium persulphate (APS) as the initiator and N,N,N’,N’-tetramethyl ethylenediamine (TEMED) and heat as the activators for APS. In this one-pot preparation, SIH was formed in a short reaction time of 10 minutes. The formed SIH was converted into hydrogel silver nanocomposite (HSN) by loading silver ions into the SIH matrix and reducing the silver ions to nanosilver with neem plant extract (Azadirachta Indica) as a green reducing agent. The formed HSN was probed with UV-Visible diffused reflectance spectroscopy (UV-Vis DRS), fourier transform infrared spectroscopy (FT-IR), high resolution scanning electron microscopy (HR-SEM), energy dispersive X-ray analysis (EDX), X-ray diffraction study (XRD), and thermogravimetric analysis (TGA). The effect of time, silver nitrate concentration and pH on the swelling behaviour of HSN and its antibacterial activity were investigated. The antibacterial studies revealed that the prepared HSN significantly decreases bacterial growth. The strong hindrance of Ago loaded hydrogel against bacterial growth and the ideal release of nanosilver into the bacterial culture makes the HSN appropriate for biomedical applications.

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Iranian Journal of Chemistry and Chemical Engineering

Articles in Press, Accepted Manuscript
Available Online from 11 September 2023

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