Application of Sulfonic Acid Functionalized Nanoporous Silica (SBA-Pr-SO3H) in the Green One-pot Synthesis of Polyhydroacridine Libraries

Document Type: Research Article

Authors

1 Department of Chemistry, Alzahra University, P.O. Box 193891176 Tehran, I.R. IRAN

2 School of Chemistry, College of Science, University of Tehran, P.O. Box 14155-6455 Tehran, I.R. IRAN

Abstract

1,8-Dioxo-decahydroacridines have been synthesized by the three-component reaction of aromatic aldehydes, aromatic amines (or ammonium acetate), and dimedone in the presence of sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) under solvent-free conditions. Excellent yields, short reaction times, mild reaction conditions, and easy work-up procedures are advantages of this green method.  

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Main Subjects


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