Boric Acid Supported on Montmorillonites as Catalysts for Synthesis of 2,3-dihydroquinazolin-4(1H)-ones

Document Type: Research Article

Authors

1 Department of Chemistry, Vel Tech High Tech Dr. Rangarajan Dr. Sakunthala Engineering College, Avadi, Chennai-600 062, INDIA

2 Department of Chemistry, College of Engineering Studies, University of Petroleum & Energy Studies (UPES), Bidholi Campus, Dehradun-248 007, INDIA

3 Department of Chemistry, Shinas College of Technology, Shinas, OMAN

Abstract

Synthesis of 2,3-dihydroquinazolin-4(1H)-ones using H3BO3/montmorillonite K10 (H3BO3/mont K10) catalyst has been reported. H3BO3/mont K10 and H3BO3/mont K30 have been prepared and used as catalysts in the reaction between anthranilamide and benzaldehyde to prepare 2-phenyl-2,3-dihydroquinazolin-4(1H)-one. The catalysts have been characterized for their physico-chemical properties by XRD, IR, BET surface analysis, TGA, SEM, and DRIFTS. H3BO3/mont K10 has shown better catalytic activity among the catalysts tested for the synthesis of 2-phenyl-2,3-dihydroquinazolin-4(1H)-one. The reaction conditions have been optimized for 2-phenyl-2,3-dihydroquinazolin-4(1H)-one and the reusability of H3BO3/mont K10 has also been investigated. Several 2,3-dihydroquinazolin-4(1H)-one derivatives have been synthesized in good to excellent yields using the optimized reaction conditions.

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