Document Type: Research Article
Department of Chemistry, University of Sistan and Baluchestan, Zahedan, I.R. IRAN
Department of Nanotechnology and Advanced Materials, Materials and Energy Research Center, Karaj, I.R. IRAN
Department of Biology and Microbiology, University of Sistan and Baluchestan, Zahedan, I.R. IRAN
Islamic Azad University, Neyshabur Branch, Neyshabur, I.R. IRAN
Seven reported xanthate ligands and their new Fe(II) complexes of formulaNa[Fe(R-OCSS)3], where R is ethyl-, propyl-, butyl-, pentyl-, Hexyl-, heptyl- and octyl-xanthate have been synthesized. They have been characterized using elemental analysis, molar conductance, FT-IR, UV-Vis and 1H NMR spectroscopic techniques and melting-, decomposition-points for ligands and complexes respectively. All the ligands and their Fe(II) complexes have been evaluated for their antimicrobial activity against four gram-positive bacteria, four gram-negative bacteria and three fungi by agar disc diffusion technique. The MIC values of the compounds exhibited significant antifungal activity but showed lower antibacterial activity. The iron(II) complexes are found to possess higher antimicrobial activity than their counterpart ligands thus improving its antimicrobial efficacy. Hydrocarbon chain length of the ligands coordinated to Fe(II) centers seemed to be important for their antifungal as well as antibacterial activities.