Heravi, M. (1992). Base Catalyzed Cyclization and Isomerization of 3-Propargylmercapto-1, 2,4-Triazine to Thiazolo [3,2-b][1,2,4]-Triazines. Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 11(2), 8-11.
Majid Heravi. "Base Catalyzed Cyclization and Isomerization of 3-Propargylmercapto-1, 2,4-Triazine to Thiazolo [3,2-b][1,2,4]-Triazines". Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 11, 2, 1992, 8-11.
Heravi, M. (1992). 'Base Catalyzed Cyclization and Isomerization of 3-Propargylmercapto-1, 2,4-Triazine to Thiazolo [3,2-b][1,2,4]-Triazines', Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 11(2), pp. 8-11.
Heravi, M. Base Catalyzed Cyclization and Isomerization of 3-Propargylmercapto-1, 2,4-Triazine to Thiazolo [3,2-b][1,2,4]-Triazines. Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 1992; 11(2): 8-11.
Base Catalyzed Cyclization and Isomerization of 3-Propargylmercapto-1, 2,4-Triazine to Thiazolo [3,2-b][1,2,4]-Triazines
Department of Chemistry, Faculty of Sciences, Ferdowsi University, Mashhad, I.R. IRAN
Abstract
Transformation of 3-propargylmercapto-6 methyl-1, 2,4-triazin- 5 (2H)- one (1; R=CH3) to 3,6- dimethyl-7H- thiazolo [3,2-b] [1, 2, 4] triazin -7- one (2) is performed under basic condition. The formation of (2) may be mainly due to the high reactivity of acetylenes towards nucleophiles and isomerization of the intermediate.
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