One Pot Synthesis of Alpha-Aminonitrile and Alpha-Amino Acid From Schiff Bases

Document Type : Research Note

Authors

Department of Chemistry, Sharif University of Technology, P.O. Box 11365-9516 Tehran, I.R. IRAN

10.30492/ijcce.1999.10475

Abstract

Addition of Potassium cyanide to a mixture of Schiff base and lithium perchlorate afforded a-aminonitriles in high yields. Addition of potassium cyanide to a methanolic solution of Schiff base and phosphoric acid afforded a-aminonitriles. When the reaction mixture was refluxed it gave a-amino acids in high yields.

Keywords

Main Subjects