Methalloporphirins Catalyze Regio and Chemoselective Silylation of Hydroxy Groups with Hexamethyldisilazane (HMDS)

Document Type : Research Note


Department of Chemistry, Faculty of Science, Shiraz University, Postcode 71454, Shiraz, I.R. IRAN


Metalloporphirins; Cu(TPP), Mn(TPP)Cl, CO(TPP), Fe(TPP)Cl, zn(TPP) and Mn(OBP)Cl catalyze region and chemoselective silylation of hydroxyl groups with HMDS. Fe(TPP)Cl is the most effective catalyst and silylation occurs immediately in its presence at room temperature.


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