Document Type: Research Article
Department of Chemistry, Faculty of Sciences, University of Tehran, Tehran, I.R. IRAN
Department of Chemistry, Faculty of Sciences,University of Tehran , Tehran, I.R. IRAN
Department of Chemistry, Hunter College, New York, New York, 10021, USA
Hoffmann-LaRoche Inc. Nutley, New Jersey 07110-1199, USA
Condensation of glyoxal, formaldehyde and anilines lead to the formation of 2,4,6,8- tetraphenyl and substituted phenyl 2,4,6,8-tetraazabicyclo [3.3.0] octanes. The reactions are sensitive to pH and temperature. Ortho derivatives of anilines do not participate in this condensation. X-ray structural determination reveals a cis-dienvelope geometery about the two fused rings.