Efficient Synthesis of a Range of Benzosubstituted Macrocyclic Diamides

Document Type: Research Article

Authors

Department of Chemistry, Shiraz University, Zip code 71454, Shiraz, I.R. IRAN

Abstract

Some new macrocyclic dibenzotetraoxadiamides, tribenzotetraoxadimides, tribenzopentaoxadiamide, tribenzohexaoxadiamide, and tetrabenzoheptaoxadiamide 15-22 have been prepared. These compounds were obtained in the macrocyclization step by reacting the diamines 6 and 7 with appropriate dicarboxylic acid dichlorides 8-14. The cyclization does not require high dilution techniques or template effect and provides the expected dilactams in high yields ranging from 63% to 81%.

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