Effect of Cyclosporin-A on the Order and Dynamics of DPPC model Membrane Systems

Document Type: Research Article

Author

Department of Chemistry, Isfahan University of Technology, Isfahan, I.R. IRAN

Abstract

Laser Raman spectroscopy has been employed to investigate the effects of cyclosporine-A on the order and dynamics of DPPC (Dipalmytoyl Phosphatidyl Choline) midel membrane system. It is shown that the addition of small amount of cyclosporine-A to a DPPC dispersion disturb the system and changes the order/disorder parameter of the model membrane.

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