TY - JOUR ID - 32092 TI - Montmorillonite Nanocomposite Hydrogel Based on Poly(acrylicacid-co-acrylamide): Polymer Carrier for Controlled Release Systems JO - Iranian Journal of Chemistry and Chemical Engineering JA - IJCCE LA - en SN - 1021-9986 AU - Zarei, Shahrbanoo AU - Rezanejade Bardajee, Ghasem AU - Sadeghi, Mohamad AD - Department of chemistry, Arak Branch, Islamic Azad University, Arak, I.R. IRAN AD - Department of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran, I.R. IRAN Y1 - 2019 PY - 2019 VL - 38 IS - 5 SP - 31 EP - 43 KW - Nanocomposite hydrogel KW - Montmorillonite KW - Starch KW - Swelling behavior KW - Release DO - 10.30492/ijcce.2019.32092 N2 - In this paper, the synthesis of new montmorillonite nanocomposite hydrogel (MMTNH) based on poly (acrylic acid-co-acrylamide) grafted onto starch, is described. Montmorillonite (MMT) as nanometer base, acrylic acid (AA) and acrylamide (AAm) as monomers, ammonium persulfate (APS) as an initiator, N,N-methylenebisacrylamide (MBA) as a crosslinker and starch as a biocompatible polymer were prepared in aqueous solution and their amounts were optimized to attain the highest water absorbance. The optimized swelling capacity in distilled water was found to be 810 g/g. A mechanism for hydrogel formation was proposed and the structure of the product was confirmed using a set of techniques including FT-IR spectroscopy, thermogravimetric analysis, scanning electron microscopy, transmission electron microscopy, atomic force microscopy, and X-ray powder diffraction. Furthermore, the swelling behaviors of the nanocomposite at different pHs, various salt with different concentrations, the mixture of solvents, were investigated. The methylene blue (MB) dye was used as model drugs to assess the loading and release by MMTNH. The pH response of this MMTNH makes it suitable for acting as a controlled delivery system. The results suggest MMTNH may find applications as promising drug delivery vehicles for drug molecules. UR - https://ijcce.ac.ir/article_32092.html L1 - https://ijcce.ac.ir/article_32092_82568371c34ce7ce3bcf2f8a27cdd171.pdf ER -