TY - JOUR ID - 26369 TI - Comparison of Two Liquid-Liquid Microextractions for the Detection of Crocin in the Saffron and Biological Samples Using UV- Vis Spectrophotometry JO - Iranian Journal of Chemistry and Chemical Engineering JA - IJCCE LA - en SN - 1021-9986 AU - Heydari, Somayeh AD - Department of Chemistry, University of Torbat-e Jam, Torbat-e Jam, I.R. IRAN Y1 - 2018 PY - 2018 VL - 37 IS - 1 SP - 99 EP - 108 KW - dispersive liquid-liquid microextraction KW - Dispersive liquid-liquid microextraction based on solidification of floating organic drop KW - Crocin KW - Saffron KW - Biological samples DO - 10.30492/ijcce.2018.26369 N2 - In this work, two approaches based on Dispersive Liquid-Liquid MicroExtraction (DLLME) and Dispersive Liquid-Liquid MicroExtraction based on Solidification of Floating Organic Drop (DLLME-SFO) were compared for the extraction and preconcentration of crocin from saffron and biological samples. Different DLLME and DLLME-SFO parameters influencing the extraction efficiency were studied and optimized. The results showed that both extraction methods exhibited good linearity, precision, enrichment factor, and detection limit. Under optimal conditions, the limits of detection were 0.008 and 0.005 ng/mL for DLLME and DLLME-SFO, respectively. The preconcentration factors were 88 and 95 for DLLME and DLLME-SFO, respectively. The applicability of the proposed methods was examined by analyzing crocin in saffron, urine and milk samples and good results were obtained. The percentage recovery values for spiked samples were between 96.4 and 99.1.   UR - https://ijcce.ac.ir/article_26369.html L1 - https://ijcce.ac.ir/article_26369_6adfcb693164b36dc860c17c6903cd4b.pdf ER -