TY - JOUR ID - 10330 TI - Selective Mono Bromination of 1,4-Dihydropyridines JO - Iranian Journal of Chemistry and Chemical Engineering JA - IJCCE LA - en SN - 1021-9986 AU - Rastgar Mirzaei, Yousef AU - Moshtaghi Zenouz, Adeleh AD - Organic Synthesis Research Lab., Faculty of Chemistry, Tabriz University, Zip code 51664, Tabriz, I.R. IRAN Y1 - 1997 PY - 1997 VL - 16 IS - 1 SP - 29 EP - 32 KW - Nifedipine analogues KW - Calcium channel antagonist KW - 1 KW - 4-Dihydropyridine KW - Bromomethyl-1 KW - 4-dihydropyridines DO - 10.30492/ijcce.1997.10330 N2 - 2-monobromomethyl 1,4-dihydropyridines is selectively synthesized by bromination of the parent compound by 1.1 equivalents of pyridinium bromide perbromide in dichloromethane/pyridine at -20 °C. The same reagent in dichloromethane at 0 °C produce the 2,6-bis(bromomethyl) 1,4-dihydropyridines. UR - https://ijcce.ac.ir/article_10330.html L1 - https://ijcce.ac.ir/article_10330_177d531e444eed09594a91daf5311df4.pdf ER -