%0 Journal Article %T Trimethyl Phosphite Mediated Simple Synthesis of Coumarins and Azacoumarins Through the Reaction of Phenols or Hydroxypyridines and Dimethyl Acetylenedicarboxylate (DMAD) or Diethyl Acetylenedicarboxylate (DEAD) %J Iranian Journal of Chemistry and Chemical Engineering %I Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR %Z 1021-9986 %A Moradi, Shahram %A Azarakhshi, Fatemeh %A Masoumi Shahi, Akbar %D 2008 %\ 12/01/2008 %V 27 %N 4 %P 35-39 %! Trimethyl Phosphite Mediated Simple Synthesis of Coumarins and Azacoumarins Through the Reaction of Phenols or Hydroxypyridines and Dimethyl Acetylenedicarboxylate (DMAD) or Diethyl Acetylenedicarboxylate (DEAD) %K 2-Oxo-2H-chromenes %K Azacoumarins %K Acetylenicester %K Aromatic substitution %K Trimethyl phosphate %R 10.30492/ijcce.2008.6936 %X Protonation of the reactive intermediate produced in theĀ  reaction between trimethyl phosphite and dimethyl acetylenedicarboxylate or diethyl acetylenedicarboxylate by resorcinol, 5-methylresorcinol, 2,5-dihydroxyacetophenone, 4-chloro-2-methylphenol, 4-chloro-3,5-dimethy-lphenol, 4-hydroxypyridine, 2-hydroxypyridine, 3-hydroxypyridine, or 8-hydroxyquinoline leads to vinylphosphonium salts, which undergo Michael addition with the conjugate base of the OH-acid to produce highly functionalized 2-oxo-2H-chromene or azacoumarins in good yields. %U https://ijcce.ac.ir/article_6936_cd9036b16a77cc53767a5929b3a780b7.pdf