%0 Journal Article %T Liquid - Liquid Extraction of 2, 3-Butanediol from Fermentation Broth %J Iranian Journal of Chemistry and Chemical Engineering %I Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR %Z 1021-9986 %A Pahlavanzadeh, Hassan %A Khayati, Gholam %A Ghaemi, Nasser %A Vasheghani-Farahani, Ebrahim %D 2012 %\ 06/01/2012 %V 31 %N 2 %P 59-63 %! Liquid - Liquid Extraction of 2, 3-Butanediol from Fermentation Broth %K Extractive fermentation %K 2 %K 3-Butanediol %K Oleyl alcohol %K Liquid-liquid Extraction %R 10.30492/ijcce.2012.5990 %X Recovery of metabolites from fermentation broth by solvent extraction can be used to optimize fermentation processes. End-product reutilization, low product concentration, large volumes of fermentation broth and the requirements for large bioreactors, in addition to the high cost largely contributed to the decline in fermentative 2, 3-butanediol production. Extraction can successfully be used for in-situ alcohol recovery in 2, 3-butanediol fermentations to increase the substrate conversion.In the present work organic extraction of 2, 3-butanediol produced by Klebsiella pneumoniae fermentation was studied to detect solvent effect on 2, 3-butanediol production and determination of efficient volume of solvent. The aim of this research was liquid-liquid extractive fermentation systems evaluation as an alternative to overcome the end product effect and to increase of 2, 3-butanediol production by K. pneumoniae because conventional fermentative production of 2, 3-butanediol by K. pneumoniae hasthe disadvantage of product reutilization by the organism. The highest 2, 3-butanediol production (23.01 g/L) achieved when 20% oleyl alcohol was used.   %U https://ijcce.ac.ir/article_5990_d700f56dafdc66e7625607273052fab0.pdf