%0 Journal Article %T The synthesis of Beta-Carbonhomologous Intermediate of Norcardicin A. A General Method for Selective Preparation of The Beta-Lactam Ring in the Presence of Free Phenolic Hydroxyl Groups %J Iranian Journal of Chemistry and Chemical Engineering %I Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR %Z 1021-9986 %A Hakimelahi, Gholam H. %A Zarrinehzad, Morteza %D 1990 %\ 06/01/1990 %V 9 %N 1 %P 25-34 %! The synthesis of Beta-Carbonhomologous Intermediate of Norcardicin A. A General Method for Selective Preparation of The Beta-Lactam Ring in the Presence of Free Phenolic Hydroxyl Groups %K Synthesis of Beta-Carbonhomologous %K Synthesis of Cis-N-[Beta-carbobenzyloxy-Beta-(p-hydroxyphenyl)ethyl]-3-phathalimido-4-styryl-2-azetidinone %K mechanisms of cis and trans-Beta-lactam ring formation %R 10.30492/ijcce.1990.12255 %X The synthesis of cis-N-[a-carbobenzyloxy-b-(p-hydroxyphenyl)ethyl]-3-phthalimido-4-styryl-2-azetidinone is described. We have found that the electron-rich Schiff bases can afford the cis-b-lactam ring even in the presence of the free hydroxyl functions. The mechanisms of cis and trans-b-lactam ring formation are discussed. The discussions are consistent with the recent publications. %U https://ijcce.ac.ir/article_12255_edcfd7861d93ee7dc51fc2988c12b33b.pdf